Physicians increasingly are called on to provide primary care for the growi
ng population of people with Alzheimer-type dementia, However, little atten
tion has been paid to the care of nondementia illnesses in this group of pa
tients. To illustrate how presence of dementia can alter the risk-benefit r
atio of treatment of a common medical problem, we present a case study in w
hich a patient with dementia developed disastrous adverse effects to a drug
commonly used to treat osteoporosis. This case and 2 composite vignettes i
lluminate how presence of dementia should influence the decision-making pro
cess for treatment of nondementia illnesses. We address issues such as decr
eased decision-making capacity, problems with reporting adverse effects, de
creased cognition leading to problems with treatment adherence, and the rol
e of screening and basic questions about acceptable burdens of treatments i
n patients with limited prognosis. We Suggest ways to improve communication
with patients with dementia in an effort to minimize complications and imp
rove care, as well as policy changes to include patients with dementia in c
linical trials.