Ocular acquired toxoplasmosis after liver transplantation

Citation
C. Chiquet et al., Ocular acquired toxoplasmosis after liver transplantation, J FR OPHTAL, 23(4), 2000, pp. 375-379
Citations number
19
Categorie Soggetti
Optalmology
Journal title
JOURNAL FRANCAIS D OPHTALMOLOGIE
ISSN journal
01815512 → ACNP
Volume
23
Issue
4
Year of publication
2000
Pages
375 - 379
Database
ISI
SICI code
0181-5512(200004)23:4<375:OATALT>2.0.ZU;2-8
Abstract
We present one case of acquired Toxoplasma gondii retinochoroiditis after l ivrer transplantation. Three weeks after receiving liver-transplant from a seropositive donor for Toxoplasma gondii, the fundus examination showed a v itreal haze and an edematous retinal lesion with retinal hemorrhages. Routi ne screening tests for uveitis were performed. The serum toxoplasmosis tite rs revealed a seroconversion for toxoplasmosis (pre-transplantation tests w ere negative). The PCR assay on aqueous humor resulted in an amplified prod uct identical to toxoplasmosis. This immunocompromised patient likely recei ved an infected hepatic transplant. The patient's ocular inflammation clear ed on 1-month pyrimethamine-sulfadiazine medication. Four months later, the patient developed a retinal detachment with massive proliferative vitreore tinopathy.