The aim of the present survey was to compare the prevalence of symptoms sug
gestive of asthma in boys and girls aged 6-7 and 13-14 years in a rural and
an urban area in the West Bank. For this purpose, the International Study
of Asthma and Allergies in Childhood (ISAAC) questionnaire was issued to 97
0 schoolchildren in the two regions. The response rate was 92.2%. The preva
lences of ever wheezing in the urban and rural areas were 16.4% and 12.0%,
respectively (p < 0.05); the 12-month prevalences of wheezing were 10.5% an
d 5.5%, respectively (p < 0.05); the prevalences of more severe wheeze were
4.5% and 1.7%, respectively (p < 0.05); and prevalences of diagnosed asthm
a were 4.2% and 2.8%, respectively (p = NS). When controlling for age by st
ratification, the significant association between prevalence rates and plac
e of residence persisted in the 13-14-year age group. These results also sh
ow that the prevalence of asthma among Palestinian children is moderately h
igh in comparison with that reported from developing countries, but lower t
han those reported from Western countries. This survey, the first epidemiol
ogical survey on asthma in the West Bank , demonstrates a marked difference
between urban and rural areas. The findings emphasize the need for further
study of the environmental determinants of the disease among Palestinian c
hildren.