An attempt of identifying MS-associated loci as a follow-up of a genomic linkage study in the Italian population

Authors
D'Alfonso, S Nistico, L Bocchio, D Bomprezzi, R Marrosu, MG Murru, MR Lai, M Massacesi, L Ballerini, C Repice, A Salvetti, M Montesperelli, C Ristori, G Trojano, M Liguori, M Gambi, D Quattrone, A Tosi, R Momigliano-Richiardi, P
Citation
S. D'Alfonso et al., An attempt of identifying MS-associated loci as a follow-up of a genomic linkage study in the Italian population, J NEUROVIRO, 6, 2000, pp. S18-S22
Citations number
13
Categorie Soggetti
Neurosciences & Behavoir
Journal title
JOURNAL OF NEUROVIROLOGY
ISSN journal
13550284 → ACNP
Volume
6
Year of publication
2000
Supplement
2
Pages
S18 - S22
Database
ISI
SICI code
1355-0284(200005)6:<S18:AAOIML>2.0.ZU;2-M
Abstract
Subsequent to a genomic linkage study on Sardinian and Continental Italian families, we considered the possibility that some of the tested microsatell ite markers showed association to MS. Markers selected on the basis of the data obtained in the original set of 70 multiplex families were tested for MS association in an additional set of 154 simplex families. A limited set of markers were further tested on an additional set of 100 simplex families . The results indicate the presence of a putative MS gene in 19q13.13.