Isolated pancreatic amylase deficiency: Probable error in maturation

Authors
Mehta, DI Wang, HH Akins, RE Wang, L Proujansky, R
Citation
Di. Mehta et al., Isolated pancreatic amylase deficiency: Probable error in maturation, J PEDIAT, 136(6), 2000, pp. 844-846
Citations number
12
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
JOURNAL OF PEDIATRICS
ISSN journal
00223476 → ACNP
Volume
136
Issue
6
Year of publication
2000
Pages
844 - 846
Database
ISI
SICI code
0022-3476(200006)136:6<844:IPADPE>2.0.ZU;2-B
Abstract
A boy with failure to thrive and isolated pancreatic amylase deficiency is described. Immunoprecipitation confirmed only salivary isoamylase in duoden al fluid at ages 20 and 33 months. Because normal pancreatic amylase messen ger RNA was detected LS reverse-transcriptase polymerase chain reaction in the fluid, failure of the normal maturation of pancreatic amylase secretion may explain the deficiency.