DEVELOPMENT OF REM AND SLOW-WAVE SLEEP IN THE RAT

Citation
Mg. Frank et Hc. Heller, DEVELOPMENT OF REM AND SLOW-WAVE SLEEP IN THE RAT, American journal of physiology. Regulatory, integrative and comparative physiology, 41(6), 1997, pp. 1792-1799
Citations number
31
Categorie Soggetti
Physiology
ISSN journal
03636119
Volume
41
Issue
6
Year of publication
1997
Pages
1792 - 1799
Database
ISI
SICI code
0363-6119(1997)41:6<1792:DORASS>2.0.ZU;2-8
Abstract
Active sleep (AS) in the neonate has been considered to be an immature form of rapid eye movement !REM) sleep, Quiet sleep !QS) has been tho ught to represent an immature form of slow wave sleep (SWS). To determ ine the relationship between the behaviorally determined states of AS and QS and electrographically determined REM sleep and SWS, we examine d sleep ontogeny in the developing rat using an experimental routine t hat permitted long-term recordings and minimized the effects of matern al separation. Under these conditions. a transient state that included electroencephalographic slow wave activity and phasic motor activity was eventually replaced with the mature SWS pattern. Our work suggests that neonatal QS is not an immature form of SWS and that AS is best c onsidered as an undifferentiated behavioral state from which both SWS and REM sleep develop.