Idiopathic salivary gland enlargement (sialadenosis) in dogs: a microscopic study

A histological, histochemical and morphometric study was performed on subma ndibular salivary glands from 13 dogs which had presented with a submandibu lar mass or swelling that proved to be a portion of non-inflammatory and no n-neoplastic submandibular salivary gland. There were no consistent changes in lectin-binding histochemistry or immunohistochemical expression of vari ous cell markers, and, in most cases, there was no measurable difference in acinar size in the affected gland. The possible explanation for the clinic al salivary gland enlargement is therefore unclear.