Predictions of index of hemolysis in shear blood flow (Effects of contact with wall and particle inertia)

This paper describes the effects of the particle inertia and the contact wi th the wall on hemolysis properties. The newly proposed methods of examinin g the inertia of red blood cells (particle) on particle path are discussed using computational fluid dynamics (CFD). In these methods, the particles a re moved by Stokes drag including effects of difference of density between plasma and internal liquid in the blood. The results of computational analy sis using these methods show that (1) the diameter of the particle (red blo od cell), that is inertia of the cells, (2) the configuration of the object ive wall boundary are important factors for this prediction. The results al so show that if the inertia and the contact with the wall are considered, t he precision of the prediction of the hemolysis properties will be improved comparing with that they are not considered.