Simulation of body surface Laplacian maps during ventricular pacing in a 3D inhomogeneous heart-torso model

A computer simulation study has been conducted to investigate the performan ce of body surface Laplacian maps (BSLMs) in localizing and imaging spatial ly separated myocardial electrical events. A cellular automaton model of ve ntricles simulates cardiac electrical activity using a two-site pacing prot ocol to induce dual simultaneously active myocardial electrical events. The heart model is embedded in a realistically shaped inhomogeneous volume con ductor. The BSLMs are numerically computed from the induced electrical acti vity in the heart model. The present computer simulation results show that the BSLM can provide better separation and localization of two regional myo cardial electrical events as compared with the body surface potential map ( BSPM).