Treatment of paraphilia and sexual aggressive impulsiveness with the LHRH-Agonist Leuprolide Acetate

Up to now there are no published results of therapy of paraphilia (Pedophil ia, Sadism) and sexual aggressive impulsiveness with LHRH-(luteinizing horm one-releasing hormone) Agonists in the Germanspeaking countries. In this re port we describe 11 patients which were treated with the LHRH-Agonist Leupr olide Acetate in a period of 12 months. The patients showed no tendency of sexuell aggressive behaviour and reported an evident reduction of pen lie e rection, ejaculation, masturbation, sexual deviant impulsiveness and phanta sies. One patient died from suicide. In combination with other treatments L HRH-Agonists seem to be a very promising alternative to cyproterone acetate and its possible carcinogene effects.