Extracorporeal lung assist (ECLA) is an established treatment of severe pul
monary failure, Since extracorporeal perfusion is applied in a long-term fa
shion in this setting, the negative impact on brood compounds is of tremend
ous importance.
Pumpless arteriovenous ECLA (aV-ECLA) is an alternatively introduced techni
que that focuses on reduced blood traumatization. However, due to determini
ng technical and physiological aspects, its clinical application is limited
to a highly selected group of patients. Membrane oxygenators with minimal
pressure gradients, as well as stable patients' haemodynamics providing a s
ufficient cardiac output, are the most important prerequisites. With respec
t to recent reports, characteristic features of aV-ECLA, with special empha
sis on its physiological background, are reviewed. Accordingly, reasonable
indications for its beneficial use are discussed.
It is concluded that aV-ECLA is a feasible technique when its limitations a
re accepted. For adequate clinical use, more data concerning indications, a
s well as time- and technique-related directions are required.