Application of derivative UV spectrophotometry for the determination of enoxacin and nalidixic acid in tablets

Authors
Hopkala, H Kowalczuk, D
Citation
H. Hopkala et D. Kowalczuk, Application of derivative UV spectrophotometry for the determination of enoxacin and nalidixic acid in tablets, PHARMAZIE, 55(6), 2000, pp. 432-435
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
55
Issue
6
Year of publication
2000
Pages
432 - 435
Database
ISI
SICI code
0031-7144(200006)55:6<432:AODUSF>2.0.ZU;2-Z
Abstract
First-, second-, third- and forth-order derivative spectrophotometric metho ds, using "peak-zero" (P-O) and "peak-peak" (P-P) techniques of measurement have been developed for the determination of enoxacin and nalidixic acid i n tablets. The calibration curves were linear in the concentration range of 2.0-12.0 mu g ml (1) for the analysed quinolones. The procedure was simple , rapid and the results were reliable.