Spinal cord compression secondary to extramedullary hematopoiesis in a patient with thalassemia

Authors
Bruneteau, G Fenelon, G Khalil, A Kanfer, A Girot, R
Citation
G. Bruneteau et al., Spinal cord compression secondary to extramedullary hematopoiesis in a patient with thalassemia, REV NEUROL, 156(5), 2000, pp. 510-513
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
REVUE NEUROLOGIQUE
ISSN journal
00353787 → ACNP
Volume
156
Issue
5
Year of publication
2000
Pages
510 - 513
Database
ISI
SICI code
0035-3787(200005)156:5<510:SCCSTE>2.0.ZU;2-J
Abstract
A 19-year-old man with homozygous beta thalassemia presented with signs of thoracic spinal cord compression secondary to extramedullary hematopoiesis. The patient was treated with hypertransfusion and hydroxyurea. After two m onths, clinical signs had resolved and magnetic resonance imaging showed si gnificant regression of the extradural mass. Pathophysiology and therapeuti c options in this condition are briefly discussed.