A synthetic study of neutral and cationic cholesteryl derivatives as gene vectors

Authors
Zhu, MZ Wei, JN Wu, QH Zheng, XQ Guo, QX
Citation
Mz. Zhu et al., A synthetic study of neutral and cationic cholesteryl derivatives as gene vectors, SYN COMMUN, 30(13), 2000, pp. 2325-2333
Citations number
8
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
13
Year of publication
2000
Pages
2325 - 2333
Database
ISI
SICI code
0039-7911(2000)30:13<2325:ASSONA>2.0.ZU;2-7
Abstract
Some novel neutral and cationic lipids bearing cholesteryl groups were synt hesized. These lipids contain ketal units as linker bonds which should be e asily biodegradable in cells.