Room temperature palladium-catalysed coupling of amino acid-derived organozinc reagents with aryl triflates

Authors
Dexter, CS Jackson, RFW Elliott, J
Citation
Cs. Dexter et al., Room temperature palladium-catalysed coupling of amino acid-derived organozinc reagents with aryl triflates, TETRAHEDRON, 56(26), 2000, pp. 4539-4540
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
26
Year of publication
2000
Pages
4539 - 4540
Database
ISI
SICI code
0040-4020(20000623)56:26<4539:RTPCOA>2.0.ZU;2-1
Abstract
Aryl triflates may be cross-coupled with the amino acid derived zinc reagen ts 1, 2 and 3 using palladium catalysis at room temperature, in the presenc e of anhydrous lithium chloride, conveniently yielding phenylalanine 4, bet a-homophenylalanine 5 and gamma-bishomophenylalanine 6 derivatives respecti vely (nine examples). (C) 2000 Elsevier Science Ltd. All rights reserved.