Citation
S. Schumann et al., Stereocontrolled backbone connection of peptides by C=C-double bonds, TETRAHEDRON, 56(25), 2000, pp. 4187-4195
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020
→ ACNP
Volume
56
Issue
25
Year of publication
2000
Pages
4187 - 4195
Database
ISI
SICI code
0040-4020(20000616)56:25<4187:SBCOPB>2.0.ZU;2-D
Abstract
Treatment of peptides containing an alpha-chloroglycine residue with trieth
ylamine and catalytic amounts of triphenylphosphine constitutes an efficien
t method for the stereoselective synthesis of amino acid and peptide dimers
bridged by a C=C-double bond. The dimers can be converted into novel pepti
de structures by standard methods of peptide synthesis. (C) 2000 Elsevier S
cience Ltd. All rights reserved.