Solid-phase synthesis of hydroxy-acids leading to macrolactones

Authors
Gagnon, R Dory, YL Deslongchamps, P
Citation
R. Gagnon et al., Solid-phase synthesis of hydroxy-acids leading to macrolactones, TETRAHEDR L, 41(24), 2000, pp. 4751-4755
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
24
Year of publication
2000
Pages
4751 - 4755
Database
ISI
SICI code
0040-4039(20000615)41:24<4751:SSOHLT>2.0.ZU;2-6
Abstract
A sequence of five chemical steps on solid support yields hydroxy-acids in a very straightforward and efficient manner. The resulting compounds can be cyclized in solution phase by forming an ester bond to produce macrolacton es. (C) 2000 Published by Elsevier Science Ltd.