Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin

Authors
Fresneda, PM Molina, P Delgado, S Bleda, JA
Citation
Pm. Fresneda et al., Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin, TETRAHEDR L, 41(24), 2000, pp. 4777-4780
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
24
Year of publication
2000
Pages
4777 - 4780
Database
ISI
SICI code
0040-4039(20000615)41:24<4777:SSTT2A>2.0.ZU;2-T
Abstract
A nine-step synthesis of 9-amino-4-methoxypyrido[3',2',4, 5]pyrrolo[1,2-c]p yrimidine, a tricyclic ring system present in the marine alkaloids variolin s is described. The natural marine products meridianins C-E have been synth esized for the first time starting from N-protected 3-acylindoles, (C) 2000 Elsevier Science Ltd. All rights reserved.