A macrocyclic receptor for the chiral recognition of hydroxycarboxylates

Authors
Tejeda, A Oliva, AI Simon, L Grande, M Caballero, MC Moran, JR
Citation
A. Tejeda et al., A macrocyclic receptor for the chiral recognition of hydroxycarboxylates, TETRAHEDR L, 41(23), 2000, pp. 4563-4566
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
23
Year of publication
2000
Pages
4563 - 4566
Database
ISI
SICI code
0040-4039(20000612)41:23<4563:AMRFTC>2.0.ZU;2-N
Abstract
Good chiral recognition of hydroxycarboxylates such as lactic or mandelic a cids has been achieved with a macrocyclic receptor, readily available from a known bis-chromenylurea and a spirobifluorene linker. Resolution of the r eceptor racemic mixture was carried out taking advantage of its complexing properties with (R)-mandelic acid tetramethylammonium salt on a TLC plate. (C) 2000 Elsevier Science Ltd, All rights reserved.