A highly effective aldol reaction mediated by Ti(O-n-Bu)(4)/t-BuOK combined reagent

Authors
Han, ZF Yorimitsu, H Shinokubo, H Oshima, K
Citation
Zf. Han et al., A highly effective aldol reaction mediated by Ti(O-n-Bu)(4)/t-BuOK combined reagent, TETRAHEDR L, 41(22), 2000, pp. 4415-4418
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
22
Year of publication
2000
Pages
4415 - 4418
Database
ISI
SICI code
0040-4039(20000608)41:22<4415:AHEARM>2.0.ZU;2-1
Abstract
A combined reagent derived from Ti(O-n-Bu)(4) and KO-t-Bu (1:1) has proved to be very effective for the self-aldol addition and also for the cross-ald ol condensation between aldehyde and alpha,beta-unsaturated aldehyde such a s 2-alkenal or 2-alkynal. (C) 2000 Elsevier Science Ltd. All rights reserve d.