Probing subtle ligand effects in the enantioselective transfer hydrogenation of ketones

Authors
Frost, CG Mendonca, P
Citation
Cg. Frost et P. Mendonca, Probing subtle ligand effects in the enantioselective transfer hydrogenation of ketones, TETRAHEDR-A, 11(9), 2000, pp. 1845-1848
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
9
Year of publication
2000
Pages
1845 - 1848
Database
ISI
SICI code
0957-4166(20000519)11:9<1845:PSLEIT>2.0.ZU;2-C
Abstract
The rational modification of an established amino-alcohol scaffold has reve aled new, highly effective ligands for the enantioselective transfer hydrog enation of acetophenone that affords the product in up to 95% ee. (C) 2000 Elsevier Science Ltd. All rights reserved.