Catalytic enantioselective reactions. Part 18: Preparation of 3-deoxy-3-N,N-dialkylamino-1,2;5,6-di-O-isopropylidene-D-altritol derivatives from D-mannitol and their applications for catalytic enantioselective addition of dialkylzinc to aldehydes
Bt. Cho et al., Catalytic enantioselective reactions. Part 18: Preparation of 3-deoxy-3-N,N-dialkylamino-1,2;5,6-di-O-isopropylidene-D-altritol derivatives from D-mannitol and their applications for catalytic enantioselective addition of dialkylzinc to aldehydes, TETRAHEDR-A, 11(10), 2000, pp. 2149-2157
A series of new chiral beta-aminoalcohols, 3-deoxy-3-N,N-dialkylamino- 1,2;
5,6-di-O-isopropylidene-D-altritol derivatives 2-4 possessing a variety of
amine substituents at the 3-position and thiol or acetylthio group at the 4
-position was prepared from D-mannitol and enantioselective additions of di
ethylzinc to aldehydes using them as chiral catalysts were examined. (C) 20
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