AZTREONAM CLAVULANIC ACID IN THE TREATMENT OF SERIOUS INFECTIONS CAUSED BY STENOTROPHOMONAS-MALTOPHILIA IN NEUTROPENIC PATIENTS - CASE-REPORTS/

Authors
SANCHEZ JEG LOPEZ MLV DECASTRO AMB SIMON JAP GUTIERREZ NG MARTIN IT GARCIARODRIGUEZ JA
Citation
Jeg. Sanchez et al., AZTREONAM CLAVULANIC ACID IN THE TREATMENT OF SERIOUS INFECTIONS CAUSED BY STENOTROPHOMONAS-MALTOPHILIA IN NEUTROPENIC PATIENTS - CASE-REPORTS/, Journal of chemotherapy, 9(3), 1997, pp. 238-240
Citations number
6
Categorie Soggetti
Oncology,"Pharmacology & Pharmacy
Journal title
Journal of chemotherapy → ACNP
ISSN journal
1120009X
Volume
9
Issue
3
Year of publication
1997
Pages
238 - 240
Database
ISI
SICI code
1120-009X(1997)9:3<238:ACAITT>2.0.ZU;2-G
Abstract
Two seriously neutropenic patients (a 23-year-old man with a promyeloc ytic acute myeloid leukemia [AML-M3] and a 77-year old male with an im mature acute myeloid leukemia [AML-M1] diagnosis) with severe infectio ns caused by Stenotrophomonas maltophilia were treated with aztreonam/ clavulanic acid (2:1) combination. In the first patient the infection was caused by a multiresistant strain and in the second, by a strain w ith poor response to trimethoprim-sulfamethoxazole and other antimicro bial agents, After treatment with aztreonam/clavulanic acid both patie nts evolved favorable.