Complete occulusion of left renal artery in pediatric-onset Takayasu's arteritis

A 16-year-old male adolescent with a 4-year history of protean clinical man ifestations such as fever, abdominal pain, back pain, erythema nodosum and uveitis developed complete occulusion of left renal artery. Although he had been suspicious of having an autoimmune disease and treated with prednisol one, a definite diagnosis was not made. Finally, an angiography disclosed s tenosis of abdominal aorta just beneath the origin of the renal arteries as well as complete occulusion of left renal artery. It has been reported tha t pediatric-onset Takayasu's arteritis sometimes shows protean clinical man ifestations as in ours. Takayasu's arteritis should be considered as one of the underlaying disease, when a child develops protean manifestations sugg esting an autoimmune disease.(C) 2000 Tohoku University Medical Press.