Specific immunotherapy with hymenoptera-venoms in pregnancy

Background: Pregnancy typically prohibits the specific immunotherapy (SIT) of various allergic conditions, with the exception of pre-existing Hymenopt era venom allergies. International consensus currently recommends the conti nuation of a well-tolerated SIT with insect venom during pregnancy, since t here is a significant risk of anaphylaxis after insect stings with potentia lly dismal outcomes for mother and fetus. Case Report: We report on a 28-year old woman, becoming pregnant during spe cific immunotherapy with Hymenoptera venom. SIT was continued during pregna ncy and a premature birth occurred at the 24th week. Discussion and Conclusion: Unfortunately, there are still conflicting opini ons in Germany regarding SIT during pregnancy, and the decision to perform such therapy is entirely based on knowledge and/or level of comfort of the primary physician. Thus, obstetricians should closely work together with an allergologist in cases of pregnant women with insect sting allergies.