DEFECTIVE NEUTROPHIL FUNCTION IN WORKERS OCCUPATIONALLY EXPOSED TO HEXACHLOROBENZENE

Authors
QUEIROZ MLS BINCOLETTO C PERLINGEIRO RCR SOUZA CA TOLEDO H
Citation
Mls. Queiroz et al., DEFECTIVE NEUTROPHIL FUNCTION IN WORKERS OCCUPATIONALLY EXPOSED TO HEXACHLOROBENZENE, Human & experimental toxicology, 16(6), 1997, pp. 322-326
Citations number
30
Categorie Soggetti
Toxicology
Journal title
Human & experimental toxicology → ACNP
ISSN journal
09603271
Volume
16
Issue
6
Year of publication
1997
Pages
322 - 326
Database
ISI
SICI code
0960-3271(1997)16:6<322:DNFIWO>2.0.ZU;2-U
Abstract
In this work rye have studied the respiratory burst and chemotaxis of polymorphonuclear leukocytes from 51 workers exposed to chlorinated co mpounds, which were compared with those of non-exposed, age- and sex-m atched invididuals. These two neutrophil functions were significantly reduced as compared to controls. No correlation was observed between t he length of exposures, hexachlorobenzene (HCB) blood concentrations a nd neutrophil chemotaxis or the extent of nitroblue tetrazolium reduct ion.