A review of medical treatment for Meniere's disease

A review of the literature on drug therapy for Meniere's disease was made u sing Medline to search for all publications between January 1978 and Septem ber 1998. A total of 152 publications were identified that specifically dea lt with medical treatment for Meniere's disease. Only betahistine and diure tics appear to have proven efficacy in double-blind studies on the long-ter m control of vertigo. No treatment has a proven beneficial effect on hearin g levels or on the long-term evolution of the disease. Recent publications have proposed a role for the intratympanic use of medication, mainly aminog lycosides, for control of vertigo. We conclude this review by proposing a s trategy for the medical treatment of Meniere's disease.