Post-breeding endometritis is a major cause of subfertility in the mare. En
dometritis is a normal event in the immediate period after mating, but the
presence of ultransonographically visible uterine fluid more than 12 h late
r is thought to be evidence of uterine pathology. Tn mares that are free of
venerally transmitted endometritis, treatment is aimed at removing the int
raluminal fluid. If the endometritis persists past day 5, when the embryo e
nters the uterine lumen, the cytotoxic environment will not be compatible w
ith pregnancy. Reproductive anatomy, defective myometrial contractility, lo
wered immune defences, overproduction of mucus, inadequate lymphatic draina
ge, or a combination of these factors will predispose the mate to post-bree
ding endometritis. (C) 2000 Elsevier Science B.V. All rights reserved.