Population control in dogs and cats is an important goal for many groups. C
ontrol measures over the years has included surgery, hormonal therapy and m
ore recently immunological control. The current presentation discusses dog
population control with an emphasis on immunologic control. Specifically, v
accination with purified zona pellucida (ZP) glycoproteins leads initially
to immunocontraception and then to the profound and irreversible changes of
immunosterilization. The preliminary studies are extremely encouraging on
developing a vaccine for lasting canine population control. (C) 2000 Elsevi
er Science B.V. All rights reserved.