Acquired amegakaryocytic thrombocytopenic purpura treated with intravenousimmunoglobulins.

Acquired amegakaryocytic thrombocytopenic purprura is a rare disorder chara cterized by severe thrombocytopenia due to the absence of bone marrow megak aryocytes, The pathogenic mechanisms of this disorder have not well defined ; consequently, several empirical therapies are used. We reported the case of a 38-year-dd mean who was hospitalized for serious bleeding syndrome. The platelet count was 10 x10(9)/L. The bone marrow aspi rate and biopsy showed the absence of megakaryocytes but otherwise normal g ranulocyte and erythroid precursors. No definable etiology has been found. After the unsuccessful use of prednisone, intravenous immunoglobulin therap y was started and resulted in favorable response.