Unmet needs in the treatment of asthmatic children and adolescents: 2

Authors
Citation
B. Bjorksten, Unmet needs in the treatment of asthmatic children and adolescents: 2, CLIN EXP AL, 30, 2000, pp. 73-76
Citations number
9
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL AND EXPERIMENTAL ALLERGY
ISSN journal
09547894 → ACNP
Volume
30
Year of publication
2000
Supplement
1
Pages
73 - 76
Database
ISI
SICI code
0954-7894(200006)30:<73:UNITTO>2.0.ZU;2-8
Abstract
The five main unmet needs in the treatment of asthma in children and adoles cents are the treatment of infants, the treatment of adolescents, the effic acy of medication, the lack of clinical trials in children and the need for prevention. Asthma is a dynamic disease that changes over time and there a re several patterns of asthma in children. One of the greatest needs is to identify those children with chronic asthma where undertreatment is more of a problem than overtreatment. Although the treatment of asthma in children is the same in principle as adults, there are several practical difficulti es with infants, such as accurately assessing lung function and administeri ng drugs. Teenage asthma creates a distinct management problem. Nor only is asthma underdiagnosed but acceptance of diagnosis and compliance is often poor. Existing therapies need to be used more effectively in adolescents. I t is particularly important to establish a partnership with teenage asthmat ics and motivate them to create their own treatment goals. This requires pa ssing on knowledge. The efficacy of asthma medication may be different in c hildren than in adults and clinical studies should be performed to optimize therapy with existing drugs. The only proven primary preventive measure to prevent wheezing and asthma is to avoid passive tobacco smoke exposure. Po ssible intervention strategies include early intervention with antiinflamma tory therapy, allergen avoidance and vaccine approaches but more of them ha ve proven efficacious. Although modern asthma treatment has improved patien t quality of life and long-term prognosis, there is still a need for furthe r improvement.