Noninvasive measurement of airway inflammation using exhaled nitric oxide and induced sputum - Current status and future use

Authors
Citation
Pe. Silkoff, Noninvasive measurement of airway inflammation using exhaled nitric oxide and induced sputum - Current status and future use, CLIN CHEST, 21(2), 2000, pp. 345
Citations number
88
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
CLINICS IN CHEST MEDICINE
ISSN journal
02725231 → ACNP
Volume
21
Issue
2
Year of publication
2000
Database
ISI
SICI code
0272-5231(200006)21:2<345:NMOAIU>2.0.ZU;2-F
Abstract
Airway inflammation is the focus of research into and therapy for asthma. T his article addresses new ways to detect and monitor airway inflammation us ing induced sputum and exhaled nitric oxide. Induced sputum can give valuab le insights into the cellular and humeral components of airway inflammation . Exhaled nitric oxide is raised in untreated asthma and falls rapidly afte r inhaled or oral corticosteroids. Together, these two new ways of monitori ng asthma promise to revolutionize the way we monitor asthma and other airw ay diseases.