Oxidation and adsorption of deoxyribonucleic acid at highly ordered pyrolytic graphite electrode

Authors
Wu, LL Zhou, JZ Luo, J Lin, ZH
Citation
Ll. Wu et al., Oxidation and adsorption of deoxyribonucleic acid at highly ordered pyrolytic graphite electrode, ELECTR ACT, 45(18), 2000, pp. 2923-2927
Citations number
13
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ELECTROCHIMICA ACTA
ISSN journal
00134686 → ACNP
Volume
45
Issue
18
Year of publication
2000
Pages
2923 - 2927
Database
ISI
SICI code
0013-4686(2000)45:18<2923:OAAODA>2.0.ZU;2-H
Abstract
It shows that calf thymus DNA(CT DNA) can be adsorbed at a highly ordered p yrolytic graphite (HOPG) electrode and detected by differential pulse volta mmetry (DPV) and electrochemical atomic force microscopy (ECAFM). It is fou nd that controlled potential pre-polarization influences largely the adsorp tion of dsDNA while it has little influence on ssDNA. It is demonstrated th at ECAFM is useful to exploit adsorption of DNA at HOPGE. The mode of adsor ption of DNA at the HOPG electrode that fits best with the experimental dat a is proposed. (C) 2000 Elsevier Science Ltd. All rights reserved.