Malignant placental site trophoblastic tumor - A rare gestational trophoblastic malignancy

Placental site trophoblastic tumor (PSTT) is a rare type of gestational tro phoblastic disease with potential malignant behavior. Prognostic factors in clude extrauterine spread, time since antecedent pregnancy, age, and (possi bly) the mitotic count. Because of low chemosensitivity, resection of the p rimary tumor is considered to be the cornerstone of adequate therapy [1,2]. If complete resection of the tumor is achieved, an excellent prognosis can be expected. In cases with distant metastases or residual disease, aggress ive multiagent chemotherapy is required. The prognosis in these cases is un favorable. Because of possibly long latency until the recurrence of PSTT, l ong-term follow-up is required.