Objectives: Analysis of HRV has been suggested as a way to study the effect
s of work-related stresses on cardiovascular autonomic regulation. The aim
of this study was to evaluate the use of HRV in the investigation of work-r
elated stressors. Methods: Cross-sectional data from an ongoing cohort stud
y were used to analyse the relationship of the potential workplace stressor
s of job-strain, noise and shift work, with HRV. Mean HRV values during sle
ep and work were calculated in 135 24-h EKG recordings. Results: Shift work
ers displayed significantly decreased SDNNi levels during sleep, compared w
ith those of the daytime workers (adjusted least square mean values: 69.3 a
nd 85.8 ms, respectively, P < 0.05). Compared with the control group report
ing low job demands and high work control (mean: 73.2), we found significan
tly elevated %LF means during work adjusted for sleep in the low demands, l
ow control group (77.9, P < 0.01), high demands, high control group (77.7,
P < 0.05) and high demands, low control group (77.7, P < 0.05). Workers rep
orting a high noise level compared with a low work noise level also display
ed an elevated adjusted mean %LF during work (78.0 and 75.3 respectively, P
< 0.06). Conclusions: The finding of a decreased SDNNi level during sleep
in shift workers compared with day workers indicated a less favourable card
iovascular autonomic regulation, which may explain in part the excess cardi
ovascular disease risk in shift workers. The elevated %LF during work in em
ployees exposed to high job strain or high noise levels indicated a direct
shift in the autonomic cardiac balance towards sympathetic dominance. We co
ncluded that the analysis of HRV may provide a useful tool in the study of
the physiological effects of work-related stresses.