We investigated the role of the basal ganglia (BG) in motor imagery in pati
ents with Huntington's disease (HD). A visually guided pointing task assess
ed whether patients could predict actual movement time (MT) through motor i
magery. Executed and imagined movements were performed when vision was cons
trained centrally, or was free to move. Participants completed a series of
imagined and actual movements, with and without central fixation, between t
wo target circles. Patients with HD and controls' imagined MTs were signifi
cantly faster than their executed MTs. In compliance with Fitt's law, both
actual and imagined MTs increased as a function of increasing task difficul
ty. We conclude that motor imagery is relatively preserved in HD.