A CALCIUM-DEPENDENT NITRIC-OXIDE SYNTHASE AND NMDA R1 GLUTAMATE-RECEPTOR IN THE INK GLAND OF SEPIA-OFFICINALIS - A HINT TO A REGULATORY ROLE OF NITRIC-OXIDE IN MELANOGENESIS

Authors
PALUMBO A DICOSMO A GESUALDO I DISCHIA M
Citation
A. Palumbo et al., A CALCIUM-DEPENDENT NITRIC-OXIDE SYNTHASE AND NMDA R1 GLUTAMATE-RECEPTOR IN THE INK GLAND OF SEPIA-OFFICINALIS - A HINT TO A REGULATORY ROLE OF NITRIC-OXIDE IN MELANOGENESIS, Biochemical and biophysical research communications, 235(2), 1997, pp. 429-432
Citations number
18
Categorie Soggetti
Biology,Biophysics
Journal title
Biochemical and biophysical research communications → ACNP
ISSN journal
0006291X
Volume
235
Issue
2
Year of publication
1997
Pages
429 - 432
Database
ISI
SICI code
0006-291X(1997)235:2<429:ACNSAN>2.0.ZU;2-O
Abstract
Histochemical, immunohistochemical, and biochemical evidence is report ed showing that the ink gland of the cuttlefish Sepia officinalis cont ains a calcium-dependent isoform of nitric oxide synthase as well as a n NMDA R1 receptor subunit localized for the most part in the immature inner cells of the epithelial layer of the gland. These results may b e taken to implicate a hitherto unrecognized regulatory role of the gl utamate-nitric oxide pathway in the maturation and metabolic activity of melanin-producing cells in the cephalopod defense system. (C) 1997 Academic Press.