Although several multidimensional models have emerged to explain the develo
pment, exacerbation and maintenance of work-related upper extremity disorde
rs and disability, there is a paucity of data on the application of these m
odels for the development of worksite-based prevention and management progr
ams. Sign language interpreting is an occupation associated with increased
risk for upper extremity symptoms. Ergonomic, work organization, work style
, and work-related and individual psychosocial factors have been demonstrat
ed to play a role in the exacerbation of symptoms and lost time in this gro
up. Therefore, it was hypothesized that an intervention directed at reducin
g the impact of these factors would be associated with reductions in the nu
mber of upper extremity cases/year and associated lost time and health care
costs in a group of full-time sign language interpreters. Subjects include
d 53 symptomatic and asymptomatic interpreters working at the National Tech
nical Institute for the Deaf The intervention (eleven 1.5-hr group sessiona
l was designed to Ij reduce musculoskeletal overexertion by reducing worklo
ad and biomechanical strain, while increasing flexibility and endurance thr
ough tailored exercise and preinterpreting "warm ups," 2) improve the abili
ty of workers to manage job stress and musculoskeletal pain, 3) reduce biom
echanical exposure through work organization and work style changes, 4) alt
er organizational sources of stress by improving supervisor's managerial sk
ills to address work related upper extremity problems and provide increased
supervisor support, and 5) educate workers and supervisors regarding the o
ptimal utilization of health care resources, given the present state of the
art in terms of clinical evaluation and management. Results indicated a 69
% reduction in the number of cases reporting upper extremity problems in th
e 3 years following the intervention. Indemnity costs were reduced by 64% a
nd were maintained over the next 2 years. Health care costs followed a simi
lar; although smaller magnitude, change. Despite this reduction, a partial
rebound in all outcome measures was observed in Year 3 postintervention. Th
is rebound followed a progressive increase in work-load over the 3-year fol
low-up period.