CZE determination of somatostatin in pharmaceutical preparations

Authors
Cartoni, GP Coccioli, F Jasionowska, R Masci, M
Citation
Gp. Cartoni et al., CZE determination of somatostatin in pharmaceutical preparations, J PHARM B, 23(1), 2000, pp. 143-146
Citations number
4
Categorie Soggetti
Chemistry & Analysis
Journal title
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
ISSN journal
07317085 → ACNP
Volume
23
Issue
1
Year of publication
2000
Pages
143 - 146
Database
ISI
SICI code
0731-7085(20000801)23:1<143:CDOSIP>2.0.ZU;2-E
Abstract
We propose a simple and accurate method for CE quantitative determination o f somatostatin in pharmaceutical preparations. The method is specific for s omatostatin as indicated by the resolution between the analyte and the anal ogue peptides which differ from somatostatin by one aminoacid. The linearit y range is from 0.02 to 0.35 mg/ml. The recovery of the somatostatin from a pharmaceutical product is about 100.0%. (C) 2000 Elsevier Science B.V. All rights reserved.