Carbamazepine-associated severe left ventricular dysfunction

Citation
C. Faisy et al., Carbamazepine-associated severe left ventricular dysfunction, J TOX-CLIN, 38(3), 2000, pp. 339-342
Citations number
11
Categorie Soggetti
Pharmacology,"Pharmacology & Toxicology
Journal title
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY
ISSN journal
07313810 → ACNP
Volume
38
Issue
3
Year of publication
2000
Pages
339 - 342
Database
ISI
SICI code
0731-3810(2000)38:3<339:CSLVD>2.0.ZU;2-Y
Abstract
Introduction: The cardiovascular effects of carbamazepine are well-known bu t left ventricular dysfunction is rarely reported. Case Report: We describe 2 cases of severe carbamazepine-associated left ventricular dysfunction du ring massive self intoxications in young patients without preexistent cardi ac disease. We compare our cases to the available literature and discuss th e mechanisms implied in the development of left ventricular dysfunction fol lowing carbamazepine overdose. Bedside echocardiography was useful in both diagnosis and treatment.