Diagnosis by electron microscopy of recessive dystrophic epidermolysis bullosa.

Inherited epidermolysis bullosa (EB) includes a number of distinctive disea ses that are characterized by the presence of fragile skin and the tendency to develop blisters and erosions. The current classification separates the types of EB on the basis of the ultrastructural level of the blisterss. Th e electron microscopy is very important for the diagnosis and in the recess ive dystrophic EB shows that the lamina densa forms the roof of the blister and that the number of anchoring fibrils are absent or reduced. We present the case of a 30 year old woman with a diagnosis of recessive dystrophic E B diagnosed by electron microscopy.