Js. Warmus et Mi. Da Silva, Polyaromatic scavenger reagents (PAHSR): A new methodology for rapid purification in solution-phase combinatorial synthesis, ORG LETT, 2(13), 2000, pp. 1807-1809
A new method of purification of solution-phase combinatorial libraries has
been developed. Development of a chemically inert polyaromatic anchor with
a reactive "scavenger reagent" (PAHSR) allows unreacted reagents and impuri
ties to be removed from a reaction by absorption of the PAHSR to charcoal a
nd simple filtration.