A novel three-component one-pot pyrimidine synthesis based upon a coupling-isomerization sequence

Authors
Muller, TJJ Braun, R Ansorge, M
Citation
Tjj. Muller et al., A novel three-component one-pot pyrimidine synthesis based upon a coupling-isomerization sequence, ORG LETT, 2(13), 2000, pp. 1967-1970
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
13
Year of publication
2000
Pages
1967 - 1970
Database
ISI
SICI code
1523-7060(20000629)2:13<1967:ANTOPS>2.0.ZU;2-3
Abstract
2,4,6-Tri(hetero)aryl substituted pyrimidines can be readily synthesized in a three component one pot process based upon a coupling-isomerization sequ ence of an electron-poor (hetero)aryl halide and a terminal propargyl alcoh ol subsequently followed by a cyclocondensation with amidinium salts.