We examined cardiovascular changes associated with intra-abdominal insuffla
tion in 20 children (mean age 6.1 +/- 4.7 years, ASA physical status I or I
I) undergoing laparoscopic surgery with general anaesthesia using echocardi
ography with a transthoracic approach. Intra-abdominal pressure never excee
ded 10 mmHg. Systolic blood pressure, diastolic blood pressure, endtidal CO
2, peak, and mean airway pressure increased during intra-abdominal insuffla
tion (P < 0.001). Pneumoperitoneum was associated with increases (P < 0.001
) in left ventricular enddiastolic volume, left ventricular end-systolic vo
lume and left ventricular endsystolic meridional wall stress. In addition,
before, during and after intra-abdominal insufflation, left ventricular fra
ctional shortening and left ventricular ejection fraction, underwent slight
, insignificant changes. Pneumoperitoneum in children has a major impact on
cardiac volumes and function, mainly through the effect on ventricular loa
d conditions. The sharp increase in intra-abdominal pressure affects both p
reload and afterload, while systolic cardiac performance remains unchanged.