J. Cravero et al., Emergence agitation in paediatric patients after sevoflurane anaesthesia and no surgery: a comparison with halothane, PAEDIATR AN, 10(4), 2000, pp. 419-424
This study was designed to compare the emergence characteristics of sevoflu
rane with halothane anaesthesia in paediatric patients having no surgical i
ntervention. We randomized 32 ASA I or II paediatric outpatients scheduled
for magnetic resonance imaging scans to receive either halothane or sevoflu
rane anaesthesia. The primary outcome measure was the percentage of patient
s with emergence agitation, as defined by two different criteria. Time to d
ischarge from the postanaesthesia care unit (PACU) and the secondary recove
ry unit (SRU) were compared. Sevoflurane patients had a greater incidence o
f emergence delirium when a high threshold for agitation was defined (33% v
s. 0%, P = 0.010) and a lower threshold for agitation was applied (80% vs.
12%, P < 0.0001). Discharge times from the PACU and the SRU were not differ
ent. We conclude that there is an increased incidence of emergence agitatio
n with sevoflurane anaesthesia compared to halothane independent of any pai
nful stimulus.