Spinal atypical teratoid/rhabdoid tumor in an infant

Atypical teratoid/rhabdoid tumor of the central nervous system in infancy a nd childhood was established as an entity based on histological, immunohist ochemical, and cytogenetic studies. We report the case of a 7-month-old gir l who presented with progressive paraplegia and hypesthesia of her legs. Im aging studies revealed a spinal cord mass occupying the entire spinal canal below the T-7 level, Through a T-12-L-3 laminectomy, the intramedullary tu mor was partially debulked. Histologically, the tumor specimen had rhabdoid cells, and immunostaining showed vimentin and cytokeratin positivity. No a bnormality of chromosome 22q was detected with the fluorescence in situ hyb ridization method. Copyright (C) 2000 S. Karger AG, Basel.