Hemoperitoneum and disseminated intravascular coagulation in two neonates with congenital bilateral neuroblastoma

We report two neonates with anemia, hemoperitoneum, and bilateral palpable abdominal masses. Both developed bleeding: a hemoperitoneum in one and visc eral hemorrhages secondary to disseminated intravascular coagulation in the other. Each child was thought to have an unusual complication of adrenal h emorrhage, as the masses were of mixed echogenicity. However, histological evaluation revealed neuroblastoma. These cases point out the diagnostic dil emma of a mixed echogenicity suprarenal mass in the neonatal period and emp hasize that local and disseminated bleeding can occur as a major manifestat ion of neuroblastoma.