Individual differences in motivations and behaviors among HIV-negative part
icipants in HIV vaccine trials remain unclear. 127 active participants in v
accine trials completed an anonymous questionnaire assessing motivations fo
r trial participation, personality las measured by the NEO-FFI), and percei
ved risk of HIV infection. Results revealed that Neuroticism was positively
related to perceived risk of HIV infection, a desire for HIV testing, and
a desire for protection from HIV as motivation for trial participation. Imp
lications for personality research in HIV vaccine trials are discussed. (C)
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