A method of imaging viscoelastic parameters with acoustic radiation force

Citation
Wf. Walker et al., A method of imaging viscoelastic parameters with acoustic radiation force, PHYS MED BI, 45(6), 2000, pp. 1437-1447
Citations number
20
Categorie Soggetti
Multidisciplinary
Journal title
PHYSICS IN MEDICINE AND BIOLOGY
ISSN journal
00319155 → ACNP
Volume
45
Issue
6
Year of publication
2000
Pages
1437 - 1447
Database
ISI
SICI code
0031-9155(200006)45:6<1437:AMOIVP>2.0.ZU;2-M
Abstract
Acoustic radiation force has been proposed as a method of interrogating the mechanical properties of tissue. One simple approach applies a series of f ocused ultrasonic pulses to generate an acoustic radiation force, then proc esses the echoes returned from these pulses to estimate the radiation-force -induced displacement as a function of time. This process can be repeated a t a number of locations to acquire data for image formation. In previous wo rk we have formed images of tissue stiffness by depicting the maximum displ acement induced at each tissue location after a finite period of insonifica tion. While these maximum displacement images are able to differentiate mat erials of disparate mechanical properties, they exploit only a fraction of the information available. In this paper we show that the time-displacement curves acquired from tissue mimicking phantoms exhibit a viscoelastic resp onse which is accurately described by the Voigt model. We describe how the viscous and elastic parameters of this model may be determined from experim ental data. Finally, we show phantom images that depict not only the maximu m local displacement, but also the viscous and elastic model parameters. Th ese images offer complementary information about the target.