Current examples for the development of urinary stone disease are disc
ussed by means of data from the literature and our own studies. Urinar
y stone disease has gained increasing significance due to changes in l
iving conditions, i.e., industrialization and malnutrition. Changes in
prevalence and incidence, the occurrence of stone types and stone loc
ation, and the manner of stone removal are explained. The importance o
f nutrition in the prevention of calcium oxalate stone disease is disc
ussed in terms of fluid intake, calcium and oxalate metabolism, and di
etary fat intake. The results of a study on a standardized mixed diet
or an ovo-lactovegetarian diet show that well-balanced nutrition with
consecutive high intake of fluids leads to a significant decrease in t
he risk for urinary stone formation (calculated as relative supersatur
ation with calcium oxalate by the computer program EQUIL).